Hruby Symposium
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Program
Thursday, 21 May 2026
Session I
9:00 a.m. – 9:45 a.m.
Harnessing Computational/AI to Shape the Next Generation of Peptide-based Drug Discovery
Ved Srivastava
Abstract
9:45 a.m. – 10:05 a.m.
Complex Is Simple — The visionary philosopher Reagent Prof. Hruby’s β-Methyl in the χ-space
Guoxia Han
Abstract
10:05 a.m. – 10:25 a.m.
Mimicking Alpha-Helices for Inhibiting Protein-Protein Interactions
Jung-Mo Ahn
Abstract
Session 2
10:45 a.m. – 11:05 a.m.
Covariation Studies of GPCRs Reveal New Opportunities for Therapeutic Intervention in Pain and Obesity
Minying Cai
Abstract
11:05 a.m. – 11:25 a.m.
Size or Shape? The Never-Ending Fairytale of Melanocortin Peptides
Paolo Grieco
Abstract
11:25 a.m. – 11:45 a.m.
Late-Stage Peptide and Protein Modification Chemistry
Michael T. Taylor
Abstract
11:45 a.m. – 12:05 p.m.
NUS Reconstruction of HNCA with Virtual Decoupling in SMILE
Jinfa Ying
Abstract
12:50 p.m. – 1:35 p.m.
Peptide Drug Hunting: Entrepreneurial Science & Technology Empowering Breakthrough Medicines
Keynote
Tomi Sawyer
Abstract
Session 3
1:35 p.m. – 1:55 p.m.
On-Resin High-Throughput Experimentation (HTE) Reaction Screening and Synthesis of Macrocyclic Peptide Libraries Leveraging Direct-to-Biology (DtB) Approaches
Ron Ferguson
Abstract
1:55 p.m. – 2:20 p.m.
Novel Dual-Acting Peptides to Inhibit Pain While Reducing Opioid Addiction
Todd W. Vanderah
Abstract
2:20 p.m. – 2:45 p.m.
Designing Glucose-Sensitive Insulin
Thomas Hoeg-Jensen
Abstract
Session 4
3:05 p.m. – 3:30 p.m.
Glycopeptide Drugs from Endogenous Peptide Neurotransmitters and Hormones
Robin Polt
Abstract
3:30 p.m. – 3:55 p.m.
A Novel Angiotensin (1-7) Agonist, PNA5, for the Treatment of Ischemic Reperfusion Injury and Cardiac Dysfunction
John P. Konhilas
Abstract
3:55 p.m. – 4:15 p.m.
Mega-Throughput Screening of Large OBOC Non-Natural Peptide Libraries and the Discovery of Synthetic Intrinsically Disordered Protein Mimics
Nathan Collins
Abstract
4:15 p.m. – 4:35 p.m.
MATE™: Biohaven’s Novel, Peptide-Based Reagents Enable the Synthesis of Homogeneous and Well-Defined Antibody Conjugates
Wes Kazmierski
Abstract
4:35 p.m. – 4:55 p.m.
Late-Breaking Talk — To Be Announced
Late-Breaking
Abstract
Friday, 22 May 2026
9:00 a.m. – 9:45 a.m.
Display Technologies for Expanding Pharmaceutical Applications of Cyclotides
Keynote
David Craik
Abstract
Session 5
9:45 a.m. – 10:20 a.m.
From OBOC Combinatorial Chemistry to Cancer Nanomedicine
Kit S. Lam
Abstract
10:20 a.m. – 10:40 a.m.
Making Proteins from Peptides: Uncovering the Role of Posttranslational Modifications in Human Disease
Matthew R. Pratt
Abstract
12:30 p.m. – 1:00 p.m.
From Hruby’s Lab to Your Benchtop: 40 Years of Automated Peptide Synthesis Made in Tucson
Robert Zitterbart
Abstract